Full publications list
2022
Dense phenotyping from electronic health records enables machine learning-based prediction of preterm birth
A Abraham, B Le, I Kosti, P Straub, DR Velez-Edwards, LK Davis, et al.
BMC medicine 20 (1), 1-21 8 2022
Leveraging electronic health record data to identify phenotypes associated with pregnancy loss may lead to improved understanding of recurrent pregnancy loss
J Roger, A Tang, S Woldemariam, T Oskotsky, T Wen, J Liu, I Kosti, B Le, et al.
Fertility and Sterility 2022
A Abraham, B Le, I Kosti, P Straub, DR Velez-Edwards, LK Davis, et al.
BMC medicine 20 (1), 1-21 8 2022
Leveraging electronic health record data to identify phenotypes associated with pregnancy loss may lead to improved understanding of recurrent pregnancy loss
J Roger, A Tang, S Woldemariam, T Oskotsky, T Wen, J Liu, I Kosti, B Le, et al.
Fertility and Sterility 2022
2021
Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer’s disease
A Taubes, P Nova, KA Zalocusky, I Kosti, M Bicak, MY Zilberter, Y Hao, et al
Nature Aging, 2021
Drugs in COVID‐19 Clinical Trials: Predicting Transporter‐Mediated Drug‐Drug Interactions Using In Vitro Assays and Real World Data
SW Yee, B Vora, T Oskotsky, ... I Kosti, ... et al.
Clinical Pharmacology & Therapeutics, 2021
Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
BL Le, G Andreoletti, ... I Kosti, ... et al.
Scientific reports , 2021
Decreased mortality rate among COVID-19 patients prescribed statins: data from electronic health records in the US
I Maric, T Oskotsky, I Kosti, B Le, RJ Wong, GM Shaw, M Sirota, et al
Frontiers in medicine, 2021
Whole-tissue deconvolution and scRNAseq analysis identify altered endometrial cellular compositions and functionality associated with endometriosis
DG Bunis, W Wang, ... I Kosti, ... et al.
Frontiers in immunology, 2021
Decreased mortality rate among covid-19 patients using statins: data from us electronic health records
T Oskotsky, I Maric, I Kosti, BL Le, RJ Wong, GM Shaw, M Sirota, et al
Journal of Investigative Medicine, 2021
A Taubes, P Nova, KA Zalocusky, I Kosti, M Bicak, MY Zilberter, Y Hao, et al
Nature Aging, 2021
Drugs in COVID‐19 Clinical Trials: Predicting Transporter‐Mediated Drug‐Drug Interactions Using In Vitro Assays and Real World Data
SW Yee, B Vora, T Oskotsky, ... I Kosti, ... et al.
Clinical Pharmacology & Therapeutics, 2021
Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19
BL Le, G Andreoletti, ... I Kosti, ... et al.
Scientific reports , 2021
Decreased mortality rate among COVID-19 patients prescribed statins: data from electronic health records in the US
I Maric, T Oskotsky, I Kosti, B Le, RJ Wong, GM Shaw, M Sirota, et al
Frontiers in medicine, 2021
Whole-tissue deconvolution and scRNAseq analysis identify altered endometrial cellular compositions and functionality associated with endometriosis
DG Bunis, W Wang, ... I Kosti, ... et al.
Frontiers in immunology, 2021
Decreased mortality rate among covid-19 patients using statins: data from us electronic health records
T Oskotsky, I Maric, I Kosti, BL Le, RJ Wong, GM Shaw, M Sirota, et al
Journal of Investigative Medicine, 2021
2020
Meta-Analysis of Vaginal Microbiome Data Provides New Insights into Preterm Birth
I Kosti, S Lyalina, KS Pollard, AJ Butte* and M Sirota*
Frontiers in Microbiology, 2020
Data Integration for Immunology
S Pineda, D Bunis, I Kosti, M Sirota
AR Biomedical Data Science, 2020
I Kosti, S Lyalina, KS Pollard, AJ Butte* and M Sirota*
Frontiers in Microbiology, 2020
Data Integration for Immunology
S Pineda, D Bunis, I Kosti, M Sirota
AR Biomedical Data Science, 2020
2018
Electronic Medical Records Enable Precision Medicine Approaches for Celiac Disease
I Kosti, M Sirota
Journal of pediatric gastroenterology and nutrition, 2018.
Global transcriptome analysis of RNA abundance regulation by ADAR in lung adenocarcinoma
MF Sharpnack, B Chen, D Aran, I Kosti, DD Sharpnack, DP Carbone, P Mallick, K Huang
EBioMedicine, 2018.
Meta-analysis of maternal and fetal transcriptomic data elucidates the role of adaptive and innate immunity in preterm birth
B Vora, A Wang, I Kosti, H Huang, I Paranjpe, TJ Woodruff, T MacKenzie, M Sirota
Frontiers in immunology, 2018.
I Kosti, M Sirota
Journal of pediatric gastroenterology and nutrition, 2018.
Global transcriptome analysis of RNA abundance regulation by ADAR in lung adenocarcinoma
MF Sharpnack, B Chen, D Aran, I Kosti, DD Sharpnack, DP Carbone, P Mallick, K Huang
EBioMedicine, 2018.
Meta-analysis of maternal and fetal transcriptomic data elucidates the role of adaptive and innate immunity in preterm birth
B Vora, A Wang, I Kosti, H Huang, I Paranjpe, TJ Woodruff, T MacKenzie, M Sirota
Frontiers in immunology, 2018.
2017
Myofibril breakdown during atrophy is a delayed response requiring the transcription factor PAX4 and desmin depolymerization
A Volodin, I Kosti, AL Goldberg and S Cohen
PNAS 2017
A Volodin, I Kosti, AL Goldberg and S Cohen
PNAS 2017
2016
Cross-tissue Analysis of Gene and Protein Expression in Normal and Cancer Tissues
I Kosti, N Jain, D Aran, AJ Butte and M Sirota
Scientific Reports, 2016
I Kosti, N Jain, D Aran, AJ Butte and M Sirota
Scientific Reports, 2016
2015
Characterization of an epigenetic signature at intragenic exons and its implication for expression
M Singer*, I Kosti*, Lior Pachter and Yael Mandel-Gutfreund,
NAR, 2015
M Singer*, I Kosti*, Lior Pachter and Yael Mandel-Gutfreund,
NAR, 2015
2014
RBPmap: a web server for mapping binding sites of RNA-binding proteins
I Paz, I Kosti, MJ Ares, M Cline and Y Mandel-Gutfreund
NAR, 2014
I Paz, I Kosti, MJ Ares, M Cline and Y Mandel-Gutfreund
NAR, 2014
2013
HnRNP F/H homologue of Trypanosoma brucei is differentially expressed in the two life stages of the parasite and regulates splicing and mRNA stability
SK Gupta*, I Kosti*, G Plaut*, A Pivko*, et al
NAR, 2013
SK Gupta*, I Kosti*, G Plaut*, A Pivko*, et al
NAR, 2013
2012
Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection
DA Martinez,…, I Kosti,…., TC White
mBio 2012
An integrated regulatory network reveals pervasive cross-regulation among transcription and splicing factors
I Kosti, P Radivojac and Y Mandel-Gutfreund
PLoS Computational Biology, 2012
Characterization of Coding Synonymous and Non-Synonymous Polymorphisms in ADAMTS13 Using Ex Vivo and In Silico Approaches
NC Edwards,…, I Kosti, …, C Kimchi-Sarfaty
PLoS ONE 2012
DA Martinez,…, I Kosti,…., TC White
mBio 2012
An integrated regulatory network reveals pervasive cross-regulation among transcription and splicing factors
I Kosti, P Radivojac and Y Mandel-Gutfreund
PLoS Computational Biology, 2012
Characterization of Coding Synonymous and Non-Synonymous Polymorphisms in ADAMTS13 Using Ex Vivo and In Silico Approaches
NC Edwards,…, I Kosti, …, C Kimchi-Sarfaty
PLoS ONE 2012
2011
ARTS the Unusual Septin: Structural and Functional aspects
Y Mandel-Gutfreund, I Kosti and S Larish
Journal of Biological Chemistry 2011
Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma
CP Kubicek,..., I Kosti,..., IV Grigoriev
Genome Biology 2011
Y Mandel-Gutfreund, I Kosti and S Larish
Journal of Biological Chemistry 2011
Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma
CP Kubicek,..., I Kosti,..., IV Grigoriev
Genome Biology 2011
2010
SFmap: A Web Server For Motif Analysis and Prediction of Splicing Factors Binding Sites
I Paz, M Akerman, I Dror, I Kosti and Y Mandel-Gutfreund
NAR, 2010
Comparative analysis of fungal protein kinases and associated domains
I Kosti, Y Mandel-Gutfreund, F Glaser and BA Horwitz
BMC genomics, 2010
I Paz, M Akerman, I Dror, I Kosti and Y Mandel-Gutfreund
NAR, 2010
Comparative analysis of fungal protein kinases and associated domains
I Kosti, Y Mandel-Gutfreund, F Glaser and BA Horwitz
BMC genomics, 2010